Immune modulation during latent herpesvirus infection
نویسندگان
چکیده
منابع مشابه
Immune System Behavior during Herpesvirus Infection in Childhood
Background: Persistently infected cells by herpesvirus (HSV, CMV, EBV) and their dysfunction are associated with different disorders. The immune and endocrine systems are involved in pathogenesis of herpesvirus infection. Changes of IFN-γ, IL-4, DHEAS and cortisol level are a part of the regulatory mechanisms of the immune and endocrine system responses in persistent herpesvirus infection. Obje...
متن کاملImmune System Behavior during Herpesvirus Infection in Childhood
The effect of hormones on immune response is a rapidly developing field. There are increasing number of studies connecting, CNS and endocrine systems to immune responses to infectious agents such as Herpes Simplex Virus (HSV). Herpes Simplex (HSV) infections causing primary and recurrent infections are the cause of a wide spectrum of diseases with symptoms changing from mucocutaneous lesions to...
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Natural killer (NK) cells were identified by their ability to kill target cells without previous sensitization. However, without an antecedent "arming" event, NK cells can recognize, but are not equipped to kill, target cells. How NK cells become armed in vivo in healthy hosts is unclear. Because latent herpesviruses are highly prevalent and alter multiple aspects of host immunity, we hypothesi...
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Kaposi's sarcoma-associated herpesvirus (KSHV) establishes life-long infection by evading clearance by the host immune system. In de novo infection and lytic replication, KSHV escapes cytotoxic T cells and NK cells through downregulation of MHC class-I and ICAM-1 molecules and associated antigens involved in forming and sustaining the immunological synapse. However, the efficacy of such mechani...
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BACKGROUND Herpes simplex virus 1 (HSV-1) and varicella zoster virus (VZV) cause extensive intra-ocular and neural infections in humans and are closely related to Felid herpes virus 1 (FeHV-1). We report the extent of intra-ocular replication and the extent and morphological aspects of neural replication during the acute and latent phases of FeHV-1 infection. Juvenile, SPF cats were inoculated ...
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ژورنال
عنوان ژورنال: Immunological Reviews
سال: 2011
ISSN: 0105-2896
DOI: 10.1111/j.1600-065x.2011.01074.x